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13. 14. 15. C a r t e r , C . D . ; Kimbrough, R . D . ; Zack, M . M . , J r . ; Phillips, P . E . T e t r a c h l o r o d i b e n z o - d i o x i n : An a c c i d e n t a l poisoning episode in horse arenas. S c i e n c e , 1975, 188, 738-740. ; Hail, A. Waste d i s p o s a l : It's a dirty b u s i n e s s . Chemical Week, March 1, 1978, pp. 25-29. Brown, C . C . Mathematical aspects of dose response s t u d i e s i n carcinogenesis: The concept of t h r e s h o l d s . Oncology, 1976, 32, 62-65.

052-00300724-0. ; ACS Symposium Series; American Chemical Society: Washington, DC, 1982. RISK ASSESSMENT A T HAZARDOUS W A S T E SITES 32 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. C a r t e r , C . D . ; Kimbrough, R . D . ; Zack, M . M . , J r . ; Phillips, P . E . T e t r a c h l o r o d i b e n z o - d i o x i n : An a c c i d e n t a l poisoning episode in horse arenas. S c i e n c e , 1975, 188, 738-740. ; Hail, A. Waste d i s p o s a l : It's a dirty b u s i n e s s . Chemical Week, March 1, 1978, pp.

ACS Symposium Series; American Chemical Society: Washington, DC, 1982. RISK ASSESSMENT A T HAZARDOUS W A S T E SITES TABLE I I Epidemiologic Evaluating Potentia Epidemiologic Issues Issues Fundamental t o Impact on E p i d e m i o l o g i c Study Expected b a s e l i n e frequency of s p e c i f i c h e a l t h e f f e c t s R e l a t i v e l y low expected f r e quency r e q u i r e s l a r g e p o p u l a t i o n f o r study, e s p e c i a l l y to detect small increases i n risk. Latency Long l a t e n c y may r e q u i r e p e r i odic or continuous long-term population followup.

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